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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1940 2
1948 2
1949 2
1951 6
1952 2
1953 2
1954 3
1955 4
1956 4
1957 7
1958 4
1959 8
1960 3
1961 3
1962 26
1963 82
1964 116
1965 47
1966 11
1967 17
1968 11
1969 8
1970 13
1971 13
1972 9
1973 12
1974 11
1975 30
1976 15
1977 17
1978 10
1979 13
1980 10
1981 10
1982 26
1983 16
1984 14
1985 19
1986 19
1987 16
1988 16
1989 17
1990 7
1991 18
1992 19
1993 13
1994 22
1995 17
1996 12
1997 16
1998 11
1999 17
2000 22
2001 14
2002 17
2003 21
2004 20
2005 21
2006 22
2007 24
2008 25
2009 22
2010 18
2011 21
2012 34
2013 48
2014 37
2015 48
2016 52
2017 50
2018 52
2019 48
2020 40
2021 37
2022 38
2023 29
2024 11

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1,510 results

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Page 1
Regulation and function of the mammalian tricarboxylic acid cycle.
Arnold PK, Finley LWS. Arnold PK, et al. J Biol Chem. 2023 Feb;299(2):102838. doi: 10.1016/j.jbc.2022.102838. Epub 2022 Dec 26. J Biol Chem. 2023. PMID: 36581208 Free PMC article. Review.
The tricarboxylic acid (TCA) cycle, otherwise known as the Krebs cycle, is a central metabolic pathway that performs the essential function of oxidizing nutrients to support cellular bioenergetics. More recently, it has become evident that TCA …
The tricarboxylic acid (TCA) cycle, otherwise known as the Krebs cycle, is a central metabolic pathway th …
Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.
Murphy MP, O'Neill LAJ. Murphy MP, et al. Cell. 2018 Aug 9;174(4):780-784. doi: 10.1016/j.cell.2018.07.030. Cell. 2018. PMID: 30096309 Free article. Review.
Krebs cycle intermediates traditionally link to oxidative phosphorylation whilst also making key cell components. ...Succinate plays an important role in inflammatory, hypoxic, and metabolic signaling, while itaconate (from another Krebs cycle intermed
Krebs cycle intermediates traditionally link to oxidative phosphorylation whilst also making key cell components. ...Succinate
The role of itaconate in host defense and inflammation.
Peace CG, O'Neill LA. Peace CG, et al. J Clin Invest. 2022 Jan 18;132(2):e148548. doi: 10.1172/JCI148548. J Clin Invest. 2022. PMID: 35040439 Free PMC article. Review.
This metabolic reprogramming supports phagocytic function, cytokine release, and ROS production that are critical to protective inflammatory responses. The Krebs cycle is a central metabolic pathway within all mammalian cell types. In activated macrophages, distinct …
This metabolic reprogramming supports phagocytic function, cytokine release, and ROS production that are critical to protective inflammatory …
Hepatic glucose and lipid metabolism.
Jones JG. Jones JG. Diabetologia. 2016 Jun;59(6):1098-103. doi: 10.1007/s00125-016-3940-5. Epub 2016 Apr 5. Diabetologia. 2016. PMID: 27048250 Review.
These parallel requirements are met by coordinated control of carbohydrate and lipid fluxes into and out of the Krebs cycle, which is highly tuned to nutrient availability and heavily regulated by insulin and glucagon. ...
These parallel requirements are met by coordinated control of carbohydrate and lipid fluxes into and out of the Krebs cycle, w …
KREBS cycle.
[No authors listed] [No authors listed] Lancet. 1960 Apr 23;1(7130):907-9. Lancet. 1960. PMID: 13857525 No abstract available.
The Krebs Uric Acid Cycle: A Forgotten Krebs Cycle.
Salway JG. Salway JG. Trends Biochem Sci. 2018 Nov;43(11):847-849. doi: 10.1016/j.tibs.2018.04.012. Epub 2018 May 26. Trends Biochem Sci. 2018. PMID: 29807701
These are (i) the ornithine cycle (urea cycle), (ii) the citric acid cycle (tricarboxylic acid or TCA cycle), and (iii) the glyoxylate cycle that was described by Krebs and Kornberg. Ironically, Kornberg, codis …
These are (i) the ornithine cycle (urea cycle), (ii) the citric acid cycle (tricarboxylic acid
The Tricarboxylic Acid Cycle as a Central Regulator of the Rate of Aging: Implications for Metabolic Interventions.
Borkum JM. Borkum JM. Adv Biol (Weinh). 2023 Jul;7(7):e2300095. doi: 10.1002/adbi.202300095. Epub 2023 May 2. Adv Biol (Weinh). 2023. PMID: 37132059 Free article. Review.
However, their benefits are limited and their connections to the underlying mechanisms of aging are not fully clear. Here, these connections are explored in terms of the tricarboxylic acid (TCA) cycle (Krebs cycle, citric acid c
However, their benefits are limited and their connections to the underlying mechanisms of aging are not fully clear. Here, these connections …
Tricarboxylic Acid Cycle Intermediates and Individual Ageing.
Kurhaluk N. Kurhaluk N. Biomolecules. 2024 Feb 22;14(3):260. doi: 10.3390/biom14030260. Biomolecules. 2024. PMID: 38540681 Free PMC article. Review.
Individual components of these effects are postulated to be related to the energy supply by tricarboxylic acid (TCA) cycle intermediates and free radical production processes. ...The findings suggest that this approach may also be useful to show that Krebs
Individual components of these effects are postulated to be related to the energy supply by tricarboxylic acid (TCA) cycle
Krebs and an alternative TCA cycle!
Doan MT, Teitell MA. Doan MT, et al. Cell Res. 2022 Jun;32(6):509-510. doi: 10.1038/s41422-022-00664-4. Cell Res. 2022. PMID: 35459937 Free PMC article. No abstract available.
Krebs Cycle Rewired: Driver of Atherosclerosis Progression?
Liang Y, Chen Y, Li L, Zhang S, Xiao J, Wei D. Liang Y, et al. Curr Med Chem. 2022;29(13):2322-2333. doi: 10.2174/0929867328666210806105246. Curr Med Chem. 2022. PMID: 34365937
The tricarboxylic acid (TCA) cycle is the center of energy metabolism in eukaryotic cells and is dynamically adjusted according to the energy needs of cells. Macrophages are activated by inflammatory stimuli, and then two breakpoints in TCA cycle lead …
The tricarboxylic acid (TCA) cycle is the center of energy metabolism in eukaryotic cells and is dynamically adjusted a …
1,510 results